Microsoft Defender MSSP Partners

Microsoft Defender is a family of security products that provides protection across endpoints, email, identity, cloud applications, and cloud workloads. The Defender product line includes Microsoft Defender for Endpoint (EDR), Defender for Office 365 (email security), Defender for Identity (AD threat detection), Defender for Cloud Apps (CASB), Defender for Cloud (cloud workload protection), and Microsoft Defender XDR for correlated cross-domain detection. Together, these products form an integrated security layer across the Microsoft ecosystem.

Microsoft Defender is one of the most widely supported security platforms among MSSPs, reflecting its large install base. Many Defender capabilities are included in Microsoft 365 E5 and similar enterprise licenses. The platform's native integration with Microsoft 365, Azure, and Entra ID provides correlated threat detection across endpoints, email, identity, and cloud workloads through the unified Defender XDR console.

Choosing a Microsoft Defender MSSP Partner

When evaluating Microsoft Defender MSSP partners, look for providers with recognized credentials such as the Microsoft Solutions Partner for Security designation, which indicates verified expertise across the Defender product family. Strong candidates should demonstrate experience operating the full Defender stack (Endpoint, Office 365, Identity, and Cloud) along with Microsoft Sentinel for SIEM and SOAR. Because Microsoft frequently updates its security platforms with renamed services, portal consolidation, and new licensing structures, an experienced provider helps your organization stay current without operational disruption.

Sentinel engineering expertise is a key differentiator among Microsoft-focused MSSPs. Ask providers how they design efficient log ingestion strategies to control Sentinel's consumption-based costs, build custom analytics rules, develop automated response playbooks, and integrate third-party data sources. For organizations with hybrid environments spanning on-premises Active Directory, Entra ID, and Azure, confirm the MSSP has experience securing both traditional Windows infrastructure and modern cloud identity systems. Whether you need fully managed security operations, co-managed Defender XDR monitoring, or help operationalizing Defender capabilities already included in your Microsoft 365 E5 licensing, prioritize providers with deep Microsoft security architecture knowledge.

Microsoft Defender Adoption

9% of MSSPs in our dataset (20 of 235) support Microsoft Defender.

160 providers managing Microsoft Defender

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Arctic Wolf logo

Arctic Wolf

Arctic Wolf delivers security operations as a concierge service, combining its cloud-native platform with a dedicated team of security experts assigned to each...

Eden Prairie, MN1000+ employeesMinutes SLA
Managed Detection & Response (MDR)SIEM ManagementVulnerability ManagementCloud Security+3 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)
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Darktrace

Darktrace delivers AI-driven managed threat detection and autonomous response services, using self-learning AI to detect and respond to novel threats across dig...

Cambridge, UK1000+ employees
Managed Detection & Response (MDR)Network Security MonitoringCloud SecurityEmail Security+2 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)
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eSentire logo

eSentire

eSentire is a global MDR leader founded in 2001, protecting 2,000+ organizations across 80+ countries with 24/7 threat detection, containment, and response.

Cambridge, Ontario, Canada500-1000 employees15 minutes SLA
Managed Detection & Response (MDR)Cloud SecurityThreat IntelligenceIncident Response+1 more
Serves: Mid-Market (201-1000), Enterprise (1000+)
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Expel logo

Expel

Expel provides transparent, technology-driven managed detection and response that gives customers full visibility into how security decisions are made and threa...

Herndon, VA500-1000 employees15 minutes SLA
Managed Detection & Response (MDR)Cloud SecurityIncident ResponseThreat Intelligence+2 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)
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Huntress logo

Huntress

Huntress provides managed security specifically for small and mid-size businesses and the MSPs that serve them, combining automated threat detection with human-...

Baltimore, MD500-1000 employees1 hour SLA
Managed Detection & Response (MDR)Endpoint ProtectionIncident ResponseThreat Intelligence+2 more
Serves: Startups (1-50), SMB (51-200), Mid-Market (201-1000)
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Palo Alto Networks Unit 42 logo

Palo Alto Networks Unit 42

Palo Alto Networks delivers managed extended detection and response through its Cortex XMDR service, backed by Unit 42 threat research and incident response exp...

Santa Clara, CA1000+ employees15 minutes SLA
Managed Detection & Response (MDR)Cloud SecurityIncident ResponsePenetration Testing+4 more
Serves: Mid-Market (201-1000), Enterprise (1000+)
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Pondurance logo

Pondurance

Pondurance is an Indianapolis-based MDR firm founded in 2008 with a US-only SOC model, delivering human-led threat hunting and 24/7 detection and response with...

Indianapolis, IN200-500 employees15 minutes SLA
Managed Detection & Response (MDR)SIEM ManagementVulnerability ManagementIncident Response+2 more
Serves: SMB (51-200), Mid-Market (201-1000)
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Red Canary

Red Canary is a managed detection and response provider that delivers outcome-focused security operations, combining its proprietary detection engine with a ded...

Denver, CO500-1000 employees
Managed Detection & Response (MDR)Endpoint ProtectionCloud SecurityThreat Intelligence+1 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)
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Sophos

Sophos MDR delivers managed detection and response built on the Sophos security ecosystem, offering both Sophos-native and multi-vendor environment support for...

Abingdon, UK1000+ employees30 minutes SLA
Managed Detection & Response (MDR)Endpoint ProtectionCloud SecurityIncident Response+4 more
Serves: Startups (1-50), SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)
Accenture Security logo

Accenture Security

Accenture Security provides managed security services as part of its global consulting and technology practice, serving large enterprises with complex, multi-na...

Dublin, Ireland1000+ employees15 minutes SLA
Managed Detection & Response (MDR)SIEM ManagementVulnerability ManagementCloud Security+5 more
Serves: Enterprise (1000+)

ActZero

ActZero provides AI-driven managed detection and response, using machine learning to deliver automated threat detection and response for SMB and mid-market orga...

Vancouver, BC, Canada50-200 employees
Managed Detection & Response (MDR)Endpoint ProtectionCloud SecurityIncident Response
Serves: Startups (1-50), SMB (51-200), Mid-Market (201-1000)

Adlumin

Adlumin provides a managed detection and response platform purpose-built for mid-market organizations, combining SIEM, UEBA, and automated response with 24/7 ma...

Washington, DC100-200 employees
Managed Detection & Response (MDR)Security Operations Center as a Service (SOCaaS)SIEM ManagementVulnerability Management+2 more
Serves: SMB (51-200), Mid-Market (201-1000)

Agio

Agio provides managed cybersecurity and IT services for financial services firms and healthcare organizations, with deep expertise in hedge fund, private equity...

New York, NY200-500 employees
Security Operations Center as a Service (SOCaaS)Endpoint ProtectionVulnerability ManagementCompliance Management+2 more
Serves: SMB (51-200), Mid-Market (201-1000)

Alert Logic

Alert Logic, now part of Fortra, provides managed detection and response with an integrated technology platform that combines SIEM, IDS, vulnerability scanning,...

Houston, TX500-1000 employees15 minutes SLA
Managed Detection & Response (MDR)SIEM ManagementVulnerability ManagementCloud Security+3 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)

Ankura

Ankura provides managed cybersecurity, digital forensics, and incident response services as a global expert services firm with deep expertise in complex investi...

Washington, DC1000+ employees
Managed Detection & Response (MDR)Incident ResponseCompliance ManagementPenetration Testing
Serves: Mid-Market (201-1000), Enterprise (1000+)
Armor Defense logo

Armor Defense

Armor Defense is a cloud-native MSSP founded in 2009 in Plano, TX, delivering managed security for cloud workloads with a strong focus on compliance, healthcare...

Plano, TX200-500 employees15 minutes SLA
Managed Detection & Response (MDR)Compliance ManagementVulnerability ManagementIncident Response+3 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)

Ascend Technologies

Ascend Technologies provides managed cybersecurity, cloud services, and IT infrastructure management for mid-market organizations across the United States.

Chicago, IL200-500 employees
Security Operations Center as a Service (SOCaaS)Endpoint ProtectionVulnerability ManagementCloud Security
Serves: SMB (51-200), Mid-Market (201-1000)

Aujas Cybersecurity

Aujas Cybersecurity provides managed security operations, identity management, and security advisory services as an Indian cybersecurity firm serving global ent...

Bangalore, India200-500 employees
Security Operations Center as a Service (SOCaaS)Identity & Access Management (IAM)Cloud SecurityVulnerability Management+1 more
Serves: Mid-Market (201-1000), Enterprise (1000+)
Avertium logo

Avertium

Avertium provides managed security services, threat detection, and cyber advisory, formed from the merger of several established regional MSSPs to create a nati...

Phoenix, AZ200-500 employees30 minutes SLA
Managed Detection & Response (MDR)SIEM ManagementVulnerability ManagementIncident Response+3 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)

BAE Systems Digital Intelligence

BAE Systems Digital Intelligence delivers managed security services, threat intelligence, and cyber defense for government and critical infrastructure clients,...

Guildford, UK1000+ employees
Managed Detection & Response (MDR)Security Operations Center as a Service (SOCaaS)Threat IntelligenceIncident Response+1 more
Serves: Enterprise (1000+)

Barracuda Networks

Barracuda Networks delivers managed XDR, email security, and network protection services, with a strong focus on enabling MSPs and MSSPs through its partner-cen...

Campbell, CA1000+ employees
Managed Detection & Response (MDR)Email SecurityEndpoint ProtectionNetwork Security Monitoring+2 more
Serves: Startups (1-50), SMB (51-200), Mid-Market (201-1000)

BDO Cybersecurity

BDO provides managed security monitoring, incident response, and cybersecurity advisory as one of the largest global accounting and professional services networ...

Chicago, IL1000+ employees
Managed Detection & Response (MDR)Incident ResponseCompliance ManagementPenetration Testing+1 more
Serves: Mid-Market (201-1000), Enterprise (1000+)
Binary Defense logo

Binary Defense

Binary Defense provides managed detection and response and SOC services with a focus on proactive threat hunting and human-driven security operations for mid-ma...

Stow, OH200-500 employees30 minutes SLA
Managed Detection & Response (MDR)Endpoint ProtectionIncident ResponseThreat Intelligence+2 more
Serves: SMB (51-200), Mid-Market (201-1000), Enterprise (1000+)

Bitlyft

Bitlyft is a US-based MDR provider delivering True MDR with 24/7/365 monitoring by US-based Tier 3 analysts, managed SIEM, SOC-as-a-Service, and the AIR automat...

Grand Rapids, MI50-200 employees
Managed Detection & Response (MDR)SIEM ManagementIncident ResponseCloud Security+3 more
Serves: SMB (51-200), Mid-Market (201-1000)